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Mutations from the ATM gene trigger ataxia–telangiectasia. The ATM gene offers Recommendations for generating a protein that can help Manage cell division and it is linked to DNA fix. This protein plays an important role in the traditional advancement and action of a number of body units, including the nervous process and immune system. T

DNA ligases seal 5′-PO4 and 3′-OH polynucleotide ends by means of three nucleotidyl transfer techniques involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are critical guardians of genomic integrity, and ligase dysfunction underlies human genetic disorder syndromes. Crystal buildings of DNA ligases bound to nucleotide and n